Patrick A. Baeuerle∥: search on Z-Library

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1

Strictly Target Cell-dependent Activation of T Cells by Bispecific Single-chain Antibody Constructs of the BiTE Class

Brischwein, Klaus, Parr, Larissa, Pflanz, Stefan, Volkland, Jörg, Lumsden, John, Klinger, Matthias, Locher, Mathias, Hammond, Scott A., Kiener, Peter, Kufer, Peter, Schlereth, Bernd, Baeuerle, Patrick

Journal:

Journal of Immunotherapy

Year:

2007

Language:

english

File:

PDF, 361 KB

english, 2007

2

A revival of bispecific antibodies

Peter Kufer, Ralf Lutterbüse, Patrick A. Baeuerle

Journal:

Trends in Biotechnology

Year:

2004

Language:

english

File:

PDF, 358 KB

english, 2004

3

Pharmacokinetic and Pharmacodynamic Relationship of Blinatumomab in Patients with Non-Hodgkin Lymphoma

Hijazi, Youssef, Klinger, Matthias, Kratzer, Andrea, Wu, Benjamin, Baeuerle, Patrick A., Kufer, Peter, Wolf, Andreas, Nagorsen, Dirk, Zhu, Min

Journal:

Current Clinical Pharmacology

Year:

2018

Language:

english

File:

PDF, 3.91 MB

english, 2018

4

CD19-/CD3-bispecific antibody of the BiTE class is far superior to tandem diabody with respect to redirected tumor cell lysis

Michael Mølhøj, Sandrine Crommer, Klaus Brischwein, Doris Rau, Mirnaalini Sriskandarajah, Patrick Hoffmann, Peter Kufer, Robert Hofmeister, Patrick A. Baeuerle

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 792 KB

english, 2007

5

Serial killing of tumor cells by cytotoxic T cells redirected with a CD19-/CD3-bispecific single-chain antibody construct

Patrick Hoffmann, Robert Hofmeister, Klaus Brischwein, Christian Brandl, Sandrine Crommer, Ralf Bargou, Christian Itin, Nadja Prang, Patrick A. Baeuerle

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 359 KB

english, 2005

6

In vitro and in vivo activity of MT201, a fully human monoclonal antibody for pancarcinoma treatment

Stefanie Naundorf, Susanne Preithner, Petra Mayer, Sandra Lippold, Andreas Wolf, Frank Hanakam, Iduna Fichtner, Peter Kufer, Tobias Raum, Gert Riethmüller, Patrick A. Baeuerle, Torsten Dreier

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 326 KB

english, 2002

7

Antiviral Activity of HIV gp120 Targeting Bispecific T Cell Engager (BiTE®) Antibody Constructs

Brozy, Johannes, Schlaepfer, Erika, Mueller, Christina K. S., Rochat, Mary-Aude, Rampini, Silvana K., Myburgh, Renier, Raum, Tobias, Kufer, Peter, Baeuerle, Patrick A., Muenz, Markus, Speck, Roberto F

Journal:

Journal of Virology

Year:

2018

Language:

english

File:

PDF, 892 KB

english, 2018

8

Immunomodulatory therapy of cancer with T cell-engaging BiTE antibody blinatumomab

Dirk Nagorsen, Patrick A. Baeuerle

Journal:

Experimental Cell Research

Year:

2011

Language:

english

File:

PDF, 542 KB

english, 2011

9

Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody

Torsten Dreier, Grit Lorenczewski, Christian Brandl, Patrick Hoffmann, Uwe Syring, Frank Hanakam, Peter Kufer, Gert Riethmuller, Ralf Bargou, Patrick A. Baeuerle

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 199 KB

english, 2002

10

Developmental and tissue-specific expression of theQ5kgene

Sabine Schwemmle, Dorian Bevec, Gottfried Brem, Manuela B. Urban, Patrick A. Baeuerle, Elisabeth H. Weiss

Journal:

Year:

1991

Language:

english

File:

PDF, 1.05 MB

english, 1991

11

Micromet: engaging immune cells for life

Evelyn Wolf, Patrick A. Baeuerle

Journal:

Drug Discovery Today

Year:

2002

Language:

english

File:

PDF, 31 KB

english, 2002

12

Interleukin-1β Uses Common and Distinct Signaling Pathways for Induction of the Interleukin-6 and Tumor Necrosis Factor α Genes in the Human Astrocytoma Cell Line U373

Klaus Lieb, Christian Kaltschmidt, Barbara Kaltschmidt, Patrick A. Baeuerle, Mathias Berger, Joachim Bauer, Bernd L. Fiebich

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 1.16 MB

english, 1996

13

Redox signalling by transcription factors NF-κB and AP-1 in lymphocytes

Klaus Schulze-Osthoff, Marek Los, Patrick A. Baeuerle

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 923 KB

english, 1995

14

Redirected Lysis of Human Melanoma Cells by a MCSP/CD3-bispecific BiTE Antibody That Engages Patient-derived T Cells

Torisu-Itakura, Hitoe, Schoellhammer, Hans F., Sim, Myung-Shin, Irie, Reiko F., Hausmann, Susanne, Raum, Tobias, Baeuerle, Patrick A., Morton, Donald L.

Journal:

Journal of Immunotherapy

Year:

2011

Language:

english

File:

PDF, 350 KB

english, 2011

15

Differential activation of transcription factors NF-ϰB and AP-1 in rat liver macrophages

Thuy-Anh Tran-Thi, Karl Decker, Patrick A. Baeuerle

Journal:

Year:

1995

Language:

english

File:

PDF, 796 KB

english, 1995

16

Pro-inflammatory signaling: Last pieces in the NF-κB puzzle?

Patrick A Baeuerle

Journal:

Current Biology

Year:

1998

Language:

english

File:

PDF, 81 KB

english, 1998

17

Productivity and Quality of Recombinant Proteins Produced by Stable CHO Cell Clones can be Predicted by Transient Expression in HEK Cells

Diepenbruck, Carolin, Klinger, Matthias, Urbig, Thomas, Baeuerle, Patrick, Neef, RÃ¼diger

Journal:

Molecular Biotechnology

Year:

2013

Language:

english

File:

PDF, 434 KB

english, 2013

18

Transcription Factor NF-κ B is Activated in Primary Neurons by Amyloid β Peptides and in Neurons Surrounding Early Plaques from Patients with Alzheimer Disease

Barbara Kaltschmidt, Martin Uherek, Benedikt Volk, Patrick A. Baeuerle and Christian Kaltschmidt

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.76 MB

english, 1997

19

Hydrogen peroxide as a potent activator of T lymphocyte functions

Marek Los, Wulf Dröge, Kirstin Stricker, Patrick A. Baeuerle, Klaus Schulze-Osthoff

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 894 KB

english, 1995

20

Therapeutic window of an EpCAM/CD3-specific BiTE antibody in mice is determined by a subpopulation of EpCAM-expressing lymphocytes that is absent in humans

Maria Amann, Matthias Friedrich, Petra Lutterbuese, Eva Vieser, Grit Lorenczewski, Laetitia Petersen, Klaus Brischwein, Peter Kufer, Roman Kischel, Patrick A. Baeuerle, Bernd Schlereth

Journal:

Cancer Immunology, Immunotherapy

Year:

2009

Language:

english

File:

PDF, 672 KB

english, 2009

21

The Genomic Response of Tumor Cells to Hypoxia and Reoxygenation : Differential Activation of Transcription Factors AP-1 and NF-κB

Rudolf A. Rupec, Patrick A. Baeuerle

Journal:

Year:

1995

Language:

english

File:

PDF, 1.01 MB

english, 1995

22

Study of Gene Regulation by NF-κB and AP-1 in Response to Reactive Oxygen Intermediates

Judith M. Müller, Rudolf A. Rupec, Patrick A. Baeuerle

Journal:

Year:

1997

Language:

english

File:

PDF, 164 KB

english, 1997

23

Correct TandAb protein

Patrick A. Baeuerle, Peter Kufer

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 72 KB

english, 2007

24

Targeting of humanized antibody D93 to sites of angiogenesis and tumor growth by binding to multiple epitopes on denatured collagens

Bruce Freimark, Derek Clark, Flavia Pernasetti, Jeff Nickel, David Myszka, Patrick A. Baeuerle, Dennis Van Epps

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 1.08 MB

english, 2007

25

Blinatumomab: A historical perspective

Dirk Nagorsen, Peter Kufer, Patrick A. Baeuerle, Ralf Bargou

Journal:

Pharmacology & Therapeutics

Year:

2012

Language:

english

File:

PDF, 1003 KB

english, 2012

26

Clinical Experience with Gene Therapy and Bispecific Antibodies for T Cell-based Therapy of Cancer

A. Baeuerle, Patrick, Itin, Christian

Journal:

Current Pharmaceutical Biotechnology

Year:

2012

Language:

english

File:

PDF, 694 KB

english, 2012

27

Myocardial gene expression of matched hibernating and control tissue from patients with ischemic left ventricular dysfunction

Dietlind Zohlnhöfer, Thomas G. Nührenberg, Felix Haas, Frank Bengel, Albert Schömig, Patrick A. Baeuerle, Markus Schwaiger

Journal:

Heart and Vessels

Year:

2008

Language:

english

File:

PDF, 683 KB

english, 2008

28

Chlorate — a potent inhibitor of protein sulfation in intact cells

Patrick A. Baeuerle, Wieland B. Huttner

Journal:

Biochemical and Biophysical Research Communications

Year:

1986

Language:

english

File:

PDF, 861 KB

english, 1986

29

Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa

Gerhard Rogler*, Korbinian Brand‡, Daniela Vogl*, Sharon Page‡, Robert Hofmeister*, Tilo Andus*, Ruth Knuechel§, Patrick A. Baeuerle∥, Jürgen Schölmerich*, Volker Gross*

Journal:

Gastroenterology

Year:

1998

Language:

english

File:

PDF, 1.72 MB

english, 1998

30

Bcl-2 Down-Regulates the Activity of Transcription Factor NF-κB Induced upon Apoptosis

Stefan Grimm, Manuel K. A. Bauer, Patrick A. Baeuerle and Klaus Schulze-Osthoff

Journal:

The Journal of Cell Biology

Year:

1996

Language:

english

File:

PDF, 3.42 MB

english, 1996

31

Bispecific T cell engaging antibody constructs targeting a universally conserved part of the viral M2 ectodomain cure and prevent influenza A virus infection

Pendzialek, Jochen, Roose, Kenny, Smet, Anouk, Schepens, Bert, Kufer, Peter, Raum, Tobias, Baeuerle, Patrick A., Muenz, Markus, Saelens, Xavier, Fiers, Walter

Journal:

Antiviral Research

Year:

2017

Language:

english

File:

PDF, 2.00 MB

english, 2017

32

Combination of rituximab with blinatumomab (MT103/MEDI-538), a T cell-engaging CD19-/CD3-bispecific antibody, for highly efficient lysis of human B lymphoma cells

Sandrine d’Argouges, Sandra Wissing, Christian Brandl, Nadja Prang, Ralf Lutterbuese, Alex Kozhich, JoAnn Suzich, Mathias Locher, Peter Kiener, Peter Kufer, Robert Hofmeister, Patrick A. Baeuerle, Ral

Journal:

Leukemia Research

Year:

2009

Language:

english

File:

PDF, 815 KB

english, 2009

33

Regulation of the transcription factors NF-κB and AP-1 by redox changes

Markus Meyer, Heike L. Pahl, Patrick A. Baeuerle

Journal:

Chemico-Biological Interactions

Year:

1994

Language:

english

File:

PDF, 561 KB

english, 1994

34

Recent advances torwards understanding redox mechanisms in the activation of nuclear factor κb

Yvonne M.W Janssen-Heininger, Matthew E Poynter, Patrick A Baeuerle

Journal:

Free Radical Biology and Medicine

Year:

2000

Language:

english

File:

PDF, 523 KB

english, 2000

35

Side-by-side analysis of five clinically tested anti-EpCAM monoclonal antibodies

Markus Münz, Alexander Murr, Majk Kvesic, Doris Rau, Susanne Mangold, Stefan Pflanz, John Lumsden, Jörg Volkland, Jan Fagerberg, Gert Riethmüller, Dominik Rüttinger, Peter Kufer, Patrick A Baeuerle, T

Journal:

Cancer Cell International

Year:

2010

Language:

english

File:

PDF, 1.25 MB

english, 2010

36

On the abundance of EpCAM on cancer stem cells

Gires, Olivier, Klein, Christoph A., Baeuerle, Patrick A.

Journal:

Nature Reviews Cancer

Year:

2009

Language:

english

File:

PDF, 130 KB

english, 2009

37

The ER-overload response: activation of NF-κB

Heike L. Pahl, Patrick A. Baeuerle

Journal:

Trends in Biochemical Sciences

Year:

1997

Language:

english

File:

PDF, 1.18 MB

english, 1997

38

Tumor necrosis factor β (TNF-β) induces binding of the NF-κB transcription factor to a high-affinity κB element in the TNF-β promoter

Messer, Gerald, Weiss, Elisabeth H., Baeuerle, Patrick A.

Journal:

Year:

1990

Language:

english

File:

PDF, 2.81 MB

english, 1990

39

Lipopolysaccharide-induced lung inflammation is inhibited by neutralization of GM-CSF

Ruzica Puljic, Ewald Benediktus, Christine Plater-Zyberk, Patrick A. Baeuerle, Stefan Szelenyi, Kay Brune, Andreas Pahl

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 464 KB

english, 2007

40

Transcriptome Analysis Reveals a Role of Interferon-γ in Human Neointima Formation

Dietlind Zohlnhöfer, Thomas Richter, Franz-Josef Neumann, Thomas Nührenberg, Rainer Wessely, Richard Brandl, Alexander Murr, Christoph A. Klein, Patrick A. Baeuerle

Journal:

Year:

2001

Language:

english

File:

PDF, 4.60 MB

english, 2001

41

Immunotherapy of lymphoma and leukemia with T-cell engaging BiTE antibody blinatumomab

Nagorsen, Dirk, Bargou, Ralf, Rüttinger, Dominik, Kufer, Peter, Baeuerle, Patrick A., Zugmaier, Gerhard

Journal:

Leukemia and Lymphoma

Year:

2009

Language:

english

File:

PDF, 350 KB

english, 2009

42

Novel anti-denatured collagen humanized antibody D93 inhibits angiogenesis and tumor growth: An extracellular matrix-based therapeutic approach

Pernasetti, Flavia, Nickel, Jeffrey, Clark, Derek, Baeuerle, Patrick, Van Epps, Dennis, Freimark, Bruce

Journal:

International Journal of Oncology

Year:

2006

Language:

english

File:

PDF, 355 KB

english, 2006

43

Bispecific T cell engager (BiTE®) antibody constructs can mediate bystander tumor cell killing

Ross, Sandra L., Sherman, Marika, McElroy, Patricia L., Lofgren, Julie A., Moody, Gordon, Baeuerle, Patrick A., Coxon, Angela, Arvedson, Tara, Shiku, Hiroshi

Journal:

Year:

2017

Language:

english

File:

PDF, 3.71 MB

english, 2017

44

Sex reversal by loss of the C–terminal transactivation domain of human SOX9

Südbeck, Peter, Schmitz, M. Lienhard, Baeuerle, Patrick A., Scherer, Gerd

Journal:

Nature Genetics

Year:

1996

File:

PDF, 409 KB

1996

45

Transcription factor NF-κB is activated in microglia during experimental autoimmune encephalomyelitis

Christian Kaltschmidt, Barbara Kaltschmidt, Joseli Lannes-Vieira, Georg W. Kreutzberg, Hartmut Wekerle, Patrick A. Baeuerle, Jochen Gehrmann

Journal:

Journal of Neuroimmunology

Year:

1994

Language:

english

File:

PDF, 1.76 MB

english, 1994

46

Part 1 || Tyrosine Sulfation Is a trans-Golgi-Specific Protein Modification

Patrick A. Baeuerle and Wieland B. Huttner

Journal:

The Journal of Cell Biology

Year:

1987

Language:

english

File:

PDF, 2.72 MB

english, 1987

47

Concentrations of EpCAM ectodomain as found in sera of cancer patients do not significantly impact redirected lysis and T-cell activation by EpCAM/CD3-bispecific BiTE antibody MT110

Petsch, Silke, Gires, Olivier, Rüttinger, Dominik, Denzel, Sabine, Lippold, Sandra, Baeuerle, Patrick A., Wolf, Andreas

Journal:

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

48

Highly Efficient Elimination of Colorectal Tumor-Initiating Cells by an EpCAM/CD3-Bispecific Antibody Engaging Human T Cells

Herrmann, Ines, Baeuerle, Patrick A., Friedrich, Matthias, Murr, Alexander, Filusch, Susanne, Rüttinger, Dominik, Majdoub, Mariam W., Sharma, Sherven, Kufer, Peter, Raum, Tobias, Münz, Markus, Hartl,

Journal:

Year:

2010

Language:

english

File:

PDF, 1.53 MB

english, 2010

49

Cytotoxic activity of novel human monoclonal antibody MT201 against primary ovarian tumor cells

Wei Xiang, Pauline Wimberger, Torsten Dreier, Joachim Diebold, Doris Mayr, Patrick A. Baeuerle, Rainer Kimmig

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2003

Language:

english

File:

PDF, 417 KB

english, 2003

50

Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB

Henkel, Thomas, Machleidt, Thomas, Alkalay, Irit, Krönke, Martin, Ben-Neriah, Yinon, Baeuerle, Patrick A.

Journal:

Year:

1993

File:

PDF, 590 KB

1993

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